Abstract
Cancer is not only the challenging disease but the treatment is so the same. Chemotherapy is the treatment plan that is included as an essential treatment which increases the chances to live in serious cancer stages and their types but chemotherapy induced cardiac dysfunction is the life-threatening complications leading to electrophysiological dysfunctions presented at Electrocardiogram. Studies have presented that Chemotherapy is the cause around 5% of cardiac-toxicities and near 4% the reason of cardiac death in cancer. This study aims to review the literature behind the effect of chemotherapy on the electrocardiogram and its alterations see at various stages and types of cancer. The research literature was extracted the data from Google scholars, PubMed, Medline, and Cochrane. Various alterations on ECG parameters that were QTc prolongation, abnormal ventricular repolarization, increased heart rate, QRS complex abnormalities and the severity to the disease was seen in the increased in stage of cancer as early the cardiac toxicity was noticed and delayed in early cancer diagnosis.
Highlights
With a newer drug development in chemotherapy in last twenty years has led to better survival and life expectancy of patients with cancer
Busulfan has shown to develop atrial fibrillation with incidence of 6.4% used in combination with cyclophosphamide [11]
Anti HER 2 Agents: Trastuzumab has an incidence of 1.2% of atrial fibrillation with administration in over 8000 patients has shown [12]
Summary
Journal of Clinical and Laboratory Research 3(3); DOI:10.31579/2768-0487/044
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