Abstract
Background: Blood viscosity (BV) reflects blood thickness and stickiness, crucial for vascular health. Elevated BV is linked to stroke risk factors, suggesting a role in transient ischemic attacks (TIA).Methods: This retrospective observational study investigated BV levels in TIA patients with and without cerebral artery stenosis. Patients admitted within 24 hours of symptom onset between March 2017 and December 2021 were included. Baseline characteristics, including demographics and vascular risk factors, were assessed. BV measurements were obtained within 24 hours of symptom onset using a scanning capillary-tube viscometer. Patients were categorized into TIA groups based on the presence or absence of cerebral artery stenosis.Results: Of the 153 TIA patients screened, 86 were included for analysis. The mean age was 62.6 years, with a predominance of hypertension (59%) and dyslipidemia (45%). Patients with cerebral artery stenosis (TIA-AT group, n=56) exhibited significantly higher BV levels within 24 hours of symptom onset compared to those without stenosis (TIA-E group, n=30). This finding suggests a potential link between underlying pathophysiological mechanisms of TIA and BV levels.Conclusion: Despite the limitations of a single-center, retrospective study, this research suggests that there is evidence of increased blood viscosity in patients with TIA who have cerebral artery stenosis, implying that blood viscosity may play a role in the pathophysiology of TIA. Further research involving larger cohorts is warranted to elucidate the precise mechanisms linking BV to TIA and to validate its utility as a prognostic marker and therapeutic target in TIA management.
Published Version (
Free)
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
