Association of carbon monoxide ratio with neutrophil-lymphocyte ratios and cardiac indicators in carbon monoxide intoxication; a pilot study

Abstract

INTRODUCTION: Carbon monoxide is still a public health problem in developing countries. Brain and heart tissues are mostly affected by intoxications. Carbon monoxide poisoning causes the development of cardiac ischemia and cardiac conduction disorders. Our aim is to study the associations of NRL with cardiac indicators in patients with acute carbon monoxide poisoning. MATERIAL AND METHODS: Patients who admitted to the E.R. between the dates 01.10.2015–01.06.2017 were examined retrospectively. Of 54 patients diagnosed with carbon monoxide intoxication, 41 patients with complete parameters and follow-ups were included in the study. Their demographic information, complete blood count, troponin and CK-MB values and carbon monoxide levels were recorded. RESULTS: Of the patients who included in the study, 18 (43.9%) were female and 23 (43.9%) were male. Their age average was 43.7 ± 18.9. Troponin, CK-MB, neutrophil-lymphocyte ratio levels of the patients were not correlated with carbon monoxide levels (respectively p = 0.238, 0.707, 0.364). Troponin levels of the patients had a positive correlation with neutrophil-lymphocyte ratio (r: 0,309, p = 0.049). CONCLUSIONS: Neutrophil-lymphocyte ratio can be used to identify an early diagnosis of cardiac impacts in carbon monoxide poisonings. However, more studies on the subject are needed.