Abstract

Objective To explore the association of adiponectin and macrovascular complica-tions in patients with type 2 diabetes mellitus. Methods Eighty - three cases of type 2 diabetes mellitus were divided into two groups (43 cases with macrovascular disease and 40 cases DM without macroangi-opathy), plasma adiponectin, HbAlc, fasting plasma glucose and plasma insulin levels were detected in all cases and were compared with those of 41 healthy people. Results Adiponectin in macroangiopathy group and DM group without macroangiopathy were significantly lower than those of healthy control group (P < 0.01). Adiponectin was also significantly decreased in DM group with macroangiopathy as com-pared with DM group without macroangiopathy (P < 0.01). Conclusions The decreased adiponectin seems to be a risk factor of type 2 diabetes and its macrovascular complication. Key words: Type 2 diabetes mellitus; Macroangiopathy ; Adiponectin

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