Association of 3-year change in sleep duration with risk of all-cause mortality in Chinese older population: A national cohort study

Abstract

BackgroundExisting evidence on the association of dynamic change in sleep duration with risk of all-cause mortality in Chinese older population is limited. We aimed to explore the association of 3-year change in sleep duration with risk of all-cause mortality in a Chinese older population. Materials and methodsA total of 5772 Chinese older participants (median age 82 years) were enrolled in the current study. Cox proportional-hazard models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for the association of 3-year change in sleep duration with risk of all-cause mortality. Subgroup analyses of the association between 3-year change in sleep duration and risk of all-cause mortality were conducted by age, sex and residence. ResultsDuring a median of 4.08 years of follow-up, death developed in 1762 participants. Compared with −1 to <1 h/day change in sleep duration, the adjusted risk of all-cause mortality with < −3 h/day change in sleep duration may increase 26% (HR = 1.26, 95% CI: 1.05−1.52); the risk of all-cause mortality with 3-year change from short to long sleep duration, or long to short sleep duration versus stable normal sleep duration status was increased about 28% and 52%, respectively (HR = 1.28, 95% CI: 1.00−1.64 and HR = 1.52, 95% CI: 1.21−1.92). Subgroup analyses demonstrated that similar significant associations were observed among participants with 65 to <85 years, men and living in city and town. ConclusionsDynamic sleep duration change was significantly associated with risk of all-cause mortality. The current study suggests that sleep duration may be a non-invasive indicator for interventions aiming to reduction risk of all-cause mortality in Chinese older population.