ASSOCIATION BETWEEN VITAMIN D AND URIC ACID AMONG NORTH CYPRUS ADULTS: FIRST PRELIMINARY REPORT

Abstract

Objective: The aim of the study is to evaluate the association between serum uric acid (SUA) and 25-OH Vitamin D (25-OH-VIT D). There is no data about the association between hyperuricemia and 25-OH-VIT D deficiency for North Cyprus. Material and Methods: A cross-sectional study was performed on 356 adults aged between 18-75 years in the North Cyprus. Patients socio-demographic information, clinical and biochemical characteristics, eating habits, and lifestyle choices were recorded. Biochemical parameters were evaluated in all patients. Data were analysed by Chi-square test, Student’s t test, and ANOVA, as appropriate. Also, the Gamma correlation coefficient was calculated for the relationship between 25-OH Vitamin D groups and the other variables. Results: The prevalence of 25-OH-VIT D deficiency was 55.9% among the patients (12.86±4.63 ng/mL), the prevalence of 25-OH-VIT D insufficiency (23.44±2.38 ng/mL) was 27%, and 25-OH-VIT D levels were sufficient in only 17.1% of the patients (36.01±5.83 ng/mL). The ANOVA results indicated statistically significant differences SUA for both male and female patients between the 25-OH-VIT D groups. According to the Gamma correlation coefficient values, 25-OH Vitamin D levels were significantly negatively correlated with SUA. Conclusion: In our study indicated a high prevalence of 25-OHVIT D deficiency and insufficiency in North Cyprus adults and we have found a significant association between SUA levels and 25-OH-VIT D. As a result, both vitamin D supplementation and uric acid-lowering therapies are important in protecting patients against future atherosclerotic diseases.