Abstract
Non-alcoholic fatty liver disease (NAFLD) is considered the hepatic manifestation of metabolic syndrome. Periodontitis, as chronic inflammatory destructive disease, is associated metabolic syndromes bidirectionally. Toothbrushing is an essential and important way to manage periodontitis through mechanical removal of biofilm at periodontal tissue. We aimed to assess the association between toothbrushing frequency and the prevalent NAFLD in nationally representative Korean adults. Among adults aged 19 years and older who participated in the Korea National Health and Nutrition Examination Survey in 2010, a total of 6,352 subjects were analyzed. NAFLD was defined as fatty liver index ≥60. Multiple logistic regression analysis was used to estimate multivariable-adjusted odds ratios (ORs) and 95% confidence intervals (CIs). An inverse association between toothbrushing frequency and NAFLD was found. The adjusted ORs (95% CIs) of NALFD was 0.56 (0.35–0.91) in the group who performed toothbrushing ≥ 3 per day compared to the group that performed toothbrushing ≤ 1 per day. For those with toothbrushing frequency ≤1 per day, the adjusted OR (95% CIs) of NAFLD was 2.26 (1.22–4.19) in smokers and 4.52 (1.97–10.38) in subjects with diabetes mellitus (DM), compared to those without the disease and with toothbrushing frequency ≥2 per day, respectively. Our results indicate that higher frequency of toothbrushing is inversely associated with NAFLD. As a modifiable oral habit, regular toothbrushing may be recommended to lower risk of NAFLD, especially in high risk groups such as smokers and diabetic patients.
Highlights
ObjectivesWe aimed to assess the association between toothbrushing frequency and the prevalent Non-alcoholic fatty liver disease (NAFLD) in nationally representative Korean adults
The prevalence of metabolic syndrome is increasing worldwide
Regarding anthropometric factors associated with obesity, the frequency of toothbrushing was inversely correlated with Body mass index (BMI) (P
Summary
We aimed to assess the association between toothbrushing frequency and the prevalent NAFLD in nationally representative Korean adults. This study aims to analyze the association between the frequency of toothbrushing and prevalent NAFLD in a nationwide representative probability sample of the Korean population
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have