Abstract
Sarcopenia is defined as an age-related loss of skeletal muscle and is associated with several health disorders. Causes of sarcopenia, which included physical inactivity, alcohol, dietary habits, and smoking, have been researched. The present study was undertaken to examine the association between reproductive span and sarcopenia in Korean women. Data obtained from 2008 to 2011 Korea National Health and Nutrition Examination Surveys (KNHANES) were analyzed. We defined sarcopenia based on the cut-off values of the Foundation for the National Institutes of Health (FNIH) sarcopenia project criteria: ASM/BMI < 0.512 for women. Reproductive span was defined as years from menarche to menopause, and we divided the 3970 study subjects into three groups by reproductive span tertile. Multivariate logistic regression analysis was used to determine adjusted ORs for the relation between reproductive span and sarcopenia. The prevalence of sarcopenia in the study was 17.7% (704 of 3970). Multiple logistic regression analysis was performed using weighted populations. After adjusting for covariates, reproductive span was found to be inversely associated with the risk of sarcopenia [Tertile 1 = 1 (reference); Tertile 2, odds ratio (OR) = 0.927, 95% confidence interval (CI) = 0.863–0.995; Tertile 3, OR = 0.854, 95% CI = 0.793–0.915].
Highlights
Sarcopenia is defined as an age-related loss of skeletal muscle and is associated with several health disorders
Research by Landi et al [5] analyzing participants in the nursing home of Rome reported that chronic disease, such as cardiovascular disease (CVD) and osteoarthritis (OA), low Body mass index (BMI), and lesser involvement in leisure physical activity were significantly associated with increased risk of sarcopenia
The means of appendicular skeletal muscle mass (ASM), ASM/BMI, and ASM/height2 were greatest in the longest reproductive span group
Summary
Sarcopenia is defined as an age-related loss of skeletal muscle and is associated with several health disorders. The present study was undertaken to examine the association between reproductive span and sarcopenia in Korean women. Sarcopenia is associated with health problems, such as mobility disorders, increased fall risk, reduced ability to perform daily activities, and loss of independence [3]. A study analyzing participants living in New. recruited young and healthy Chinese participants living in Hong Kong and reported that underweight (low BMI) was significantly related with an increased ratio of sarcopenia. Research by Landi et al [5] analyzing participants in the nursing home of Rome reported that chronic disease, such as cardiovascular disease (CVD) and osteoarthritis (OA), low BMI, and lesser involvement in leisure physical activity were significantly associated with increased risk of sarcopenia
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