Abstract
INTRODUCTION: The relationship between high body fat (BF) and outcomes in pancreatic operation has not been studied in the literature. Therefore, the purpose of the study was to identify the association between BF and outcomes after pancreaticoduodenectomy (PD). METHODS: A retrospective analysis of the 2019 NSQIP database was performed. Patients were categorized into obese and nonobese groups based on BF percentage. We matched the 2 groups based on propensity score matching in a 1:1 ratio. The primary outcomes measure was mortality. Secondary outcomes measure was complication, including pancreatic fistula. RESULTS: After propensity score matching in a 1:1 ratio, there were 670 patients in the obese group and 670 patients in the nonobese group. Obese patients were more likely to have superficial surgical site infection (7% vs 4.4%; p = 0.04), and pulmonary embolism (3.4% vs 0.2%; p = 0.02), organ space surgical site infection (20.1% vs 13.9%; p = 0.002); rate of biochemical leak (9.5% vs 5%; p = 0.001) and grade B/C postoperative pancreatic fistula (16.2% vs 10.4%; p = 0.001). There was no difference in mortality between the 2 groups (2.1% vs1.1%; p = 0.1; Table).TableCONCLUSION: Percent BF may help surgeons improve risk stratification, project patient-reported functional outcomes, and better educate obese patients regarding postoperative expectations before undergoing pancreatic resection.
Published Version
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