Abstract
Association Between Depression and Recurrence of Peptic Ulcer Disease in Older Chinese Patients after Helicobacter Pylori Eradication: A Three-Year Study
Highlights
Depression is a stress-related mood disorder with a chronic course of emotional dysregulation and depressive cognition[1] that affects approximately 14.3% of the total global older population[2]
peptic ulcer disease (PUD) recurrence rate was higher in patients with self-reported depression (10.9%) than those without (6.2%)
Similar results were yielded on the association between diagnosed depression and PUD recurrence
Summary
Depression is a stress-related mood disorder with a chronic course of emotional dysregulation and depressive cognition[1] that affects approximately 14.3% of the total global older population[2]. Depression has been rated as a potential contributor to PUD, it remains unknown whether it plays a part in PUD recurrence or whether H. pylori eradication therapy achieves comparable effect on PUD recurrence among depressed and non-depressed older patients. Both Helicobacter pylori-infected peptic ulcer disease (PUD) and depression are common in older adults. H. helicobacter eradication has significantly reduced the risk of PUD recurrence, it remains unknown whether such therapy achieves comparable effect among older patients with and without depression
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