Abstract
Introduction: The level of collateral compensation plays a pivotal role in chronic symptomatic intracranial vertebrobasilar stenosis (IVBS). This study aimed to evaluate the association between cerebrovascular risk factors and collateral compensation in chronic symptomatic IVBS. Methods: This single-center cross-sectional study retrospectively reviewed 238 patients with angiographically demonstrated IVBS and divided them into good collateral compensation (GCC) group (collateral grade: 3–4, n = 110) and poor collateral compensation (PCC) group (collateral grade: 0–2, n = 128). The demographic information, laboratory tests, and clinical data of the two groups were compared and assessed using univariate logistic regression. Multivariate logistic regression was employed to analyze the independent related factors of collateral compensation. Results: Hyperlipidemia, high-density lipoprotein (HDL), and fasting blood glucose (FBG) were significantly different between the two groups. Multivariate logistic regression analysis revealed that HDL (odds ratio [OR]: 1.134, 95% confidence interval [CI]: 1.081–1.190), FBG (OR: 0.945, 95% CI: 0.925–0.964), and hyperlipidemia (OR: 0.261, 95% CI: 0.129–0.527) were statistically independent related factors of collateral compensation. The receiver-operating characteristic (ROC) analysis provided cutoff values of 34 mg/dL and 135 mg/dL for HDL and FBG associated with GCC and PCC. Conclusion: Higher HDL levels are associated with higher incidence of GCC, whereas higher FBG levels and hyperlipidemia are associated with higher incidence of PCC.
Full Text
Topics from this Paper
- Collateral Compensation
- Intracranial Vertebrobasilar Stenosis
- Cerebrovascular Risk Factors
- Collateral Grade
- Fasting Blood Glucose + Show 5 more
Create a personalized feed of these topics
Get StartedTalk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callSimilar Papers
- Stroke
- Apr 30, 2009
- Cerebrovascular Diseases
- Apr 25, 2012
- Stroke
- Jun 21, 2007
- The Lancet. Neurology
- Apr 22, 2020
- World Neurosurgery
- Aug 15, 2015
- Stroke
- Apr 26, 2012
- JAMA
- Aug 9, 2022
- Stroke
- Nov 1, 2015
- Journal of neurology
- Feb 25, 2020
- Chinese Journal of Neuromedicine
- Aug 15, 2019
- Frontiers in neurology
- May 31, 2021
- AJNR. American journal of neuroradiology
- Mar 16, 2017
- Journal of Stroke and Cerebrovascular Diseases
- Aug 8, 2014
European Neurology
- European Neurology
- Nov 10, 2023
- European Neurology
- Nov 7, 2023
- European Neurology
- Nov 3, 2023
- European Neurology
- Oct 26, 2023
- European Neurology
- Oct 23, 2023
- European Neurology
- Oct 17, 2023
- European Neurology
- Sep 30, 2023
- European Neurology
- Sep 25, 2023
- European Neurology
- Sep 6, 2023
- European Neurology
- Sep 1, 2023