Abstract

Retinal laser photocoagulation (LP) is commonly used to treat Diabetic Macular Edema. Yet, it is impossible with current lasers to prevent some degree of damage to healthy surrounding tissues. We evaluate through simulation the improvement in thermal confinement of the photocoagulation effects, using Adaptive Optics (AO), a technology that corrects eye’s aberrations in real-time, to assist LP system. Based on experimental ocular aberrations data and realistic retinal diffusion model, we simulate the photocoagulation operation and compare LP thermal confinement in laser systems without and with AO correction. Resulting sizes of thermal damage show an improvement of depth confinement, from a 300μm extension with current systems, to a 70μm depth size (limited to therapeutic target) with AO corrected system. These results underline the need of AO for focal LP to ensure thermal depth confinement and guarantee safe operation.

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