Abstract

Background Rheumatoid arthritis (RA) is a sore public prolonged arthropathy of indefinite etiology. Objective To explore the sera concentrations of neopterin (NPT), interleukin-6 (IL-6), interleukin-1β (IL-1β), tumor necrosis factor alpha (TNF-α), high sensitivity C-reactive protein (hs-CRP) and matrix metalloproteinase-9 (MMP-9) in RA patients. Methods The work involved 40 RA Iraqi patients and 40 healthy control (HC) matched by age and sex. Sera concentrations of neopterin, TNF- α, IL-1β, IL-6, MMP-9 and hs-CRP were estimated by commercially available ELISA kit. Results Sera concentrations of neopterin, IL-1β, IL-6, MMP-9, TNF-α and hs-CRP were importantly greater (P

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