Assessment of the Impact of a Multistrain Probiotic on the Quantity of Saliva in Completely Edentulous Patients: An Observational Study

Abstract

Abstract Background: Probiotics are being used to treat oral infections, for instance, periodontitis, caries, fungal infections, and halitosis. Probiotics play a significant role in the overall health of infants, teenagers, adults, and the elderly. However, there is scarce literature regarding its role in completely edentulous patients. Aim: The aim of this study was to assess the impact of multistrain probiotics on the quantity of saliva in completely edentulous patients. Materials and Methods: A total of 52 patients were recruited for the study, who were completely edentulous and wearing removable complete denture prostheses. These patients were divided into two groups. Group I (experimental) patients on multistrained probiotics named Lee-Biotic (Leeford Healthcare Ltd.) and Group II (control) consisted of patients who were not prescribed any probiotics. Saliva samples of all the patients were collected at the baseline, after 2 months, and after 3 months. The complete data were formulated systematically on the Microsoft Excel sheet, and then, it was analyzed using the Statistical Package for the Social Sciences version 21. Results: The mean value of the amount of saliva at the baseline in probiotic and nonprobiotic groups was 2.042 ml and 0.888 ml, respectively (P < 0.001 for both). After 3 months, there was a significant increase in the amount of saliva; i.e. for the probiotic group, it was 2.219 ml, and for nonprobiotic, it was 1.273 ml. Conclusion: Commercially available multistrain probiotic supplements increased the quantity of saliva in edentulous patients who were old denture wearers.