Abstract
The article is devoted to the study of the capabilities of the EG-2990Zi video gastroscope combined with the EPK-i7000 Pentax video processor in the process of comparative assessment of the effectiveness of using narrow-band video imaging with optical magnification in diagnosing certain diseases of upper gastrointestinal, namely, the esophagus, gaster, and duodenum. In particular, the method of comparative assessment of the mucous coat condition and morphological criteria in patients with Barrett's esophagus, as one of the serious complications of gastroesophageal reflux disease, is considered when performing narrow-band video imaging with optical magnification compared to a routine endoscopic examination technique. At the second stage, endoscopic indices and morphological diagnostic criteria in patients with ulcers and cicatricial deformity of the gaster and duodenum were compared. The final stage is connected with the study of the state of the mucous coat and morphological criteria in patients with polyps of the stomach and duodenum. The result of a comparative analysis of the findings obtained using these methods enables the early detection of changes in the mucous coat of the esophagus, preceding neoplastic ones when coinciding with the morphological conclusion in patients with the above diseases. The main points of scientific novelty include the following: a clear diagnostic algorithm has been first proposed for diseases of upper gastrointestinal diseases, taking into account the use of innovative technologies combined with a morphological study of biopsy material, which differs from routine endoscopic examination only in white light using a logical structure of study of the effectiveness of various endoscopic imaging visualization modes in terms of detailing of the micrograph and angioarchitecture of the mucous coat during the identification of spread and extent of manifestation of various chronic pathologies of the esophagus, gaster and duodenum; it has been proposed to assess the inter-relation between the data of endoscopic examinations and morphological criteria within the independent main and control groups, differing in the use of correlation analysis by the Spearman criterion and allowing to statistically substantiate the advantages of narrow-band imaging with high resolution in matters of early detection of changes in the mucous coat of the esophagus, gaster, duodenum, preceding neoplastic ones.
Published Version
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