ASSESSMENT OF THE EFFECT OF AEROSOL DISINFECTION OF NANOSILVER AND HYDROPEROXIDE AG+ AT CAN THO UNIVERSITY OF MEDICINE AND PHARMACY

Abstract

Background: One of the crucial methods for lowering hospital infections is air disinfection. Because the airborne contagion environment is difficult to control, the development of effective air disinfectants is critical to maintaining a safe air environment and preventing respiratory infections. At the Hospital of Can Tho University of Medicine and Pharmacy, nanosilver and hydroperoxide Ag+ are two different kinds of airborne infection control, so an analytical cross-sectional study was conducted with objectives: to compare the disinfection efficacy of two solutions, nanosilver and 5% Hydroperoxide - 0.005% Ag+, and to assess the efficacy of the silver nano solution and 5% Hydroperoxide - 0.005% Ag+ solution in disinfecting hospital air. Materials and methods: This study was conducted on 156 air microbiological samples in 13 wards at the Can Tho University of Medicine and Pharmacy Hospital using Koch's dust deposition method based on the principle of allowing dust to settle on the surface of nutrient agar boxes for a certain period. Data analysis using SPSS 26.0 software. Results: After disinfecting the rooms with nanosilver, the air quality was good in 69.23% of cases and pretty in 30.07%. With 5% Hydroperoxide - 0.005% Ag+, the number of rooms with good air quality was 15.39%, with pretty air was 69.23, and with poor air was 15.39%. Nanosilver can eradicate the fungus from Sabouraud Agar medium, and the density after disinfection was lower than before; the difference was not statistically significant (p>0.05). Moreover, on Macconkey Agar and Blood Agar medium, bacterial density after disinfecting by nanosilver was decreased; the difference was statistically significant (p < 0.05). Nanosilver reduced the bacterial density in 4 types of rooms better than 5% Hydroperoxide - 0.005% Ag+ solution. However, the difference was not statistically significant (p > 0.05). Conclusions: Nanosilver can be used to disinfect the hospital air as an alternative to 5% Hydroperoxide - 0.005% Ag+. Nanosilver disinfects well on gram-negative and gram-positive bacteria. Additional methods for improving the antifungal impact of nanosilver are required.