Abstract
Introduction: To assess the effect of total thyroidectomy on Serum progesterone and Serum prolactin present in patients with thyroid carcinoma. Method: This is a hospital-based prospective study carried out between November 2020 to November 2022 on patients diagnosed with a case of carcinoma thyroid who were admitted to J.N. Medical college and hospital. This study was done in the Department of Surgery, Jawaharlal Nehru Medical College and Rajiv Gandhi Centre of Diabetes and Endocrinology, Aligarh Muslim University, Aligarh. The patient's blood samples were collected and assessed for serum progesterone and serum prolactin (S. PRL) prior to and after 3 months postoperatively after total thyroidectomy. Result: There was an increase in the value of S. PRL. There was no change in the value of S. Progesterone. Conclusion: There was a significant change in the hormonal status after thyroidectomy. Serum PRL increased and Serum Progesterone showed no change. To our best knowledge, this was the first of a kind study to evaluate hormones following thyroidectomy in cancer patients.
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