Abstract

Antimicrobial therapy (AMT) is one of the principal problems in practice of the modern dentist. Mass visits to doctors for dental care, the prevalence of dental diseases among people from all walks of life, a unique quantitative and qualitative composition of the oral microflora, uncontrolled use of antimicrobials by patients results in increased resistance of microorganisms to antimicrobial medicines and increased number of cross-infection among dental office visitors. This article highlights the results of the study designed to assess knowledge of senior dental students of medical schools and dental residents on the main issues of antibiotic therapy and the empirical use of antimicrobials for treatment of respiratory disorders. Dental students of Belgorod have come into the study. According to the inquiry, 21.2% of dental students and 12.8% of dental residents were able to correctly choose the pharmacological group of antibiotics. 47.5% of students and 43.8% of residents decided to change the antibiotic due to the absence of clinical response within two to three days. 35% of dental students and 37.5% of the dental residents re-inquired believe that antibiotics should be replaced even in case of the positive result from their use. 16.7% of dental students managed to correctly choose all pharmacologically irrational combinations of antimicrobials, 17.2% of dental residents answered correctly after having been re-inquired. 25.6% of students and 31.2% of residents managed to completely make the empirical assignment of the AMT in case of respiratory infection. Only 50% of students and 62.5% of residents decided that their knowledge of the AMT is insufficient for the future work in the field of health care, and they need to make additional educational efforts related to the topic.

Highlights

  • According to statistical projections, by 2050, a number of fatalities affected by the diseases induced by drug resistant bacteria may keep increasing 10 million people annually [1]

  • Students should put down their year of study and major, choose whether they are questioned for the first or second time, and answer the following six principal questions regarding antimicrobial therapy: 1) define the pharmacological group of some drugs; 2) choose pharmacologically unreasonable combination(s) of drugs; 3) define the terms of antibiotics change in case of positive clinical treatment effect; 4) define the terms of antibiotics change in case of negative clinical treatment effect; 5) choose unreasonable antibiotics for empiric treatment of typical respiratory infections; 6) assess the necessity of additional educational events of antimicrobial therapy

  • Discussion of Results survey and the second one, most respondents had Despite completion of courses Pharmacology and difficulties when identifying the pharmacological group

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Summary

Introduction

By 2050, a number of fatalities affected by the diseases induced by drug resistant bacteria may keep increasing 10 million people annually [1]. In 2012, mortality from an infectious pathology was about 13 million people worldwide [2], about 700,000 of them, at the lowest estimate, died from resistant microorganisms [3]. The mass antibiotics intake has resulted in a heavy drop of microorganism sensitivity to these medications. The chemical industry which grew rapidly in discovering antibiotics since 1940s has significantly cut its development rates as soon as a new millennium began [4]. Today the doctor has no more than three to four active antibiotics to prescribe, RESEARCH RESULT: PHARMACOLOGY AND CLINICAL PHARMACOLOGY. Research result: 52 pharmacology and clinical pharmacology.

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