Abstract
The study aims to design and evaluate oral insulin for the purpose of achieving the following criteria: effectiveness in controlling blood sugar when taking insulin orally, palatability of the oral dose characteristics in terms of shape, color, smell and taste to be acceptable, especially for children. Stability of oral insulin against intestinal metabolism achieves constant bioavailability as well as oral doses are eligible to all diabetic patients. The oral nano polymer insulin (NPI) was assessed by GC mass, FTIR, electrophoresis, melting point, fluorescence labeling, microscopy, calorimetric, albumin binding assay and hydrophobicity test. The overall in vivo findings showed that NPI had onset of action 35+15 min and 5+1.5 hr duration of action with oral efficacy of 34+4% of that for intraperitoneal (IP) route. The pharmaceutical properties were convenient for oral use.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
