Assessment Of Factors Associated With PPV23 Vaccine Uptake Among Young Adults With Asthma In Olmsted County, MN

Abstract

T U E S D A Y 877 Assessment Of Factors Associated With PPV23 Vaccine Uptake Among Young Adults With Asthma In Olmsted County, MN Maria J. Bachman, Medical Student, Joshua Gauger, Medical Student, Dr. Chriss Derauf, MD, Dr. Slavica Katusic, MD, Jen Rand-Weaver, YuBin Choi, Elizabeth Krusemark, Dr. Young J. Juhn, MD, MPH; Mayo Medical School, Rochester, MN, Mayo Medical School, Dept of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN. RATIONALE: Since Oct 2008, the United States’ Advisory Committee on Immunization Practices (ACIP) has recommended a single dose of 23Valent Pneumococcal Polysaccharide vaccine (PPV-23) to asthmatics ages 19-64 years. Currently, neither PPV23 vaccine uptake rate in asthmatics nor factors associatedwith uptake have been assessed under the 2008ACIP guidelines. Objective: To determine PPV-23 vaccine uptake rate among young adults with asthma and factors associated. METHODS: The study was designed as a cross sectional study. We determined the PPV23 uptake rate during the study period (between November 1 and October 31, 2012) among asthmatics of the 1988-1989 Olmsted County Birth Cohort after the ACIP recommendations were released. Asthma status was ascertained by ICD-9 code (493). By using retrospective chart review, we obtained PPV23 vaccination history and other pertinent variables. RESULTS: Therewere 371 asthmatics in the birth cohort at the time of the new PPV23 recommendation. Of the 371 subjects, 291 eligible subjects (78.4%)were enrolled. The PPV23 uptake ratewas only 22.7% (66/291). A lower educational level of subjects (p50.007), subjects’ employment status (p50.021), the greater number of general medical examinations during the study period (p<0.001), the greater number of asthma-related visits during the study period(p<0.001), and poor asthma controls were associated with a higher PPV23 vaccine uptake rate. CONCLUSIONS: The low PPV23 uptake rate among young adults with asthma is concerning, given the increased risk of serious pneumococcal disease among asthmatics. General medical examinations and asthmarelated outpatient visits might be an important opportunity to vaccinate young adults with asthma.