Abstract
Background: Incidence of ischemic stroke in younger patients in increasing leading to higher morbidity and mortality. Data on carotid intimal medial thickness (CIMT) as atherosclerotic marker in young ischemic stroke patients are scarce.
 Aims and Objective: To evaluate bilateral CIMT thickness and its correlation with various CVD risk factors in young ischemic stroke patients.
 Methods: Total 40 patients (15 to 45 age group) and age matched 40 controls were taken. Demographic profile and risk factors were evaluated. All subjects were taken for CIMT assessment by B mode ultrasonography scan in multiangle measurements in the common carotid artery (CCA), carotid bifurcation (BIF) and internal carotid artery (ICA).
 Results: 72.5% of patients were in 35- 45 years age group. Stroke incidence was higher in male. Age specific value of CIMT was higher in all cases as compared to age matched controls in all age group. (p? 0.01) Increasing age, smoking and hypertension were significantly associated with higher bilateral CIMT.
 Conclusion: Ischemic stroke young population is associated with increased CIMT. Risk factors burden is contributory in speeding up atherosclerotic process leading to higher CIMT with multiple co morbidities.
 Keywords: carotid intimal medial thickness, carotid bifurcation, ischemic stroke
Highlights
Stroke is one of the leading causes of mortality and morbidity worldwide
[9] carotid intimal medial thickness (CIMT) is indirect tool for detection of subclinical atherosclerosis, and by assessing both carotids we can improve the prediction of future atherosclerotic events. [10]
In this study we have measured both carotids IMT and was found to be significantly higher among cases (0.575±0.134 mm and 0.603±0.123mm) as compared to controls (0.483±0.078mm and 0.495±0.088mm, p≤ 0.05), which persisted among different age groups
Summary
Stroke is one of the leading causes of mortality and morbidity worldwide. In the world approximately 20 million people each year suffer from stroke and of these 5 million do not survive. [1] Developing countries account for about 85% of global deaths from stroke [2, 3]. Men are more likely to have a stroke than women; the male/female sex ratio for India is 7:1 [4] more recently it has been estimated that 12% of all strokes occur in those less than 40 years age. It has been seen in carotid intimal medial thickness (CIMT) measured by ultrasound is predictor of atherosclerosis progression and subsequent stroke in older age group. [8] present case control study is designed to assess CIMT in ischemic stroke in young patients Relationship between CIMT and ischemic stroke in young population is not well established. [8] present case control study is designed to assess CIMT in ischemic stroke in young patients
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