Assessment of bone quality. Bone quality and osteoporosis treatment

Abstract

Anti-resorptive agents are useful for prevent osteoporotic fractures in postmenopausal women because they protect bone architecture. However, long duration of strong suppression of bone resorption may cause severe suppressed bone turnover, which results in reduced bone material properties such as homogenous distribution of mineralization or increased microdamage accumulation. Appropriate suppression of bone remodeling is a key for anti-resorptive treatments of osteoporosis to maintain or improve bone quality.