Abstract
The aim of this article is to provide an overview of central post-stroke pain (CPSP). CPSP is a specific type of neuropathic pain that is caused by disruption to the normal pain pathways within the brain following stroke. The normal pain pathways and mechanisms of CPSP are outlined here, and the importance of a comprehensive pain assessment and a multidisciplinary approach to management are considered. CPSP is more difficult to treat than nociceptive pain and can cause considerable suffering. Moreover, it can have a significant impact on the patient's engagement with rehabilitation and on their psychological wellbeing. There is wide variability in individual response to pharmacological treatment, from significant benefit to little or no benefit. Non-pharmacological treatments are sometimes employed in medication-resistant cases, and include motor cortex stimulation and deep brain stimulation. However, evidence for their use is limited.
Published Version
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