Abstract
MIP technology has successfully produced quantitative HER2 copy number (HER2CN) data. Studies have shown high concordance between this emerging technology and conventional methods such as fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC). OncoScan, the device behind MIP technology, appraises tumor percentage in the form of percent aberrant cells (%AC). However, inability to assess tumor heterogeneity, extensive stroma within the tumor, and prominent in situ …
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