Abstract
Tick-borne encephalitis (TBE) is a natural focal viral neuroinfection vastly spread in the mid-latitude climate zone of theEurasia. Lethal cases and disability related to TBE determine its high epidemiological significance as well as underlie undiminished attention to prevent it in endemic territories. At the same time, TBE epidemiologic features significantly differ in various geographic areas. Importantly, Republic Sakha (Yakutia) is not among TBE endemic areas in theRussian Federation. However, in the last decade an increased incidence of ixodic tick bites was registered in the Republic Sakha. A pattern of pathogen-specific population immunity is one of the most valuable criteria for assessing magnitude of epidemic process in TBE foci. Hence, our study was aimed at assessing natural herd immunity TBEV in Republic Sakha associated with elevated incidence of tick bite visits. Here, we analyzed the data regarding the rate of tick attacks in the period of 2001–2007 in Republic Sakha. Residents and individuals unvaccinated against TBEV in the city ofYakutskas well as various administrative regions were examined to record the peak incidence of tick attacks. It was found that a range of the administrative regions recording with registered of ixodic tick attacks and elevated incidence of tick bites was expanded. Moreover, the top incidence of tick bites was annually recorded in the south regions of the republic Aldanian, Neryungri, Olyekminsk, Leninsk, Khangalassky districts, city ofYakutskand its suburbs. Furthermore, TBEV-specific immunoglobulins were detected in 5.7±0.68% of the residents examined suggesting about contacts with the pathogen. In addition, the peak count of seropositive people (8.9±1.85%) was identified in Namsky district located in the central part of the republic. Overall, detection rate of TBEV-specific antibodies among general adult population (6.9±0.95%) was significantly higher compared to those observed in children (3.9±0.89%, р 0.05). no significant differences in urban (5.8±1.12%) vs. rural population (5.63±0.84%) was found.
Highlights
Central Office of the Federal Service for Surveillance on Costumer Rights Protection and Human Wellbeing, Republic Sakha (Yakutia), Yakutsk, Russian Federation b
Table 2. 2009–2017 prevalence of tick-born encephalitis virus antigen in ticks detached after bite in Republic
Однако для прогнозирования развития ситуации по клещевого вирусного энцефалита (КВЭ) на территории республики и определения степени ее эндемичности необходимо изучение обилия и уровня инфицированности иксодовых клещей, выявление резервуаров вируса КЭ в природных очагах, изучение напряженности иммунитета к возбудителю у сельскохозяйственных животных и продолжение исследований иммунологической структуры населения
Summary
В то же время на территории республики в последнее десятилетие отмечается рост показателей обращаемости населения по поводу присасывания иксодовых клещей. Поэтому целью настоящего исследования стала оценка состояния естественного популяционного иммунитета к вирусу клещевого энцефалита у населения Республики Саха (Якутия) в условиях роста показателей обращаемости по поводу присасывания клеща. Якутска и административных районов республики с регистрацией наибольшего количества обращений населения по поводу присасывания клещей. В ходе наблюдения отмечено расширение перечня административных территорий, где были зарегистрированы случаи нападения иксодовых клещей и рост общего количества обращений населения по поводу присасывания клеща. 680000, Russian Federation, Khabarovsk, Shevchenko str., 2, Khabarovsk Research Institute of Epidemiology and Microbiology. Библиографическое описание: Драгомерецкая А.Г., Игнатьева М.Е., Троценко О.Е., Мжельская Т.В., Будацыренова Л.В., Григорьева В.И., Романова А.П. Оценка состояния естественного популяционного иммунитета к вирусу клещевого энцефалита у населения Республики Саха (Якутия) // Инфекция и иммунитет. Central Office of the Federal Service for Surveillance on Costumer Rights Protection and Human Wellbeing, Republic Sakha (Yakutia), Yakutsk, Russian Federation b
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
