Abstract

Irrespective of its etiology, emergency surgical abdominal exploration (EAE) is considered a high-risk procedure with mortality rates exceeding 20%. The aim of this study was to evaluate differences in outcomes in patients who required EAE due to complications of complex elective abdominal procedures and those who required EAE due to high-risk primary abdominal emergencies. Patients undergoing EAE for acute surgical complications of complex abdominal elective surgical procedures (N = 293; Elective group) and patients undergoing EAE for high-risk primary abdominal emergencies (N = 776; Emergency group) from 2012 to 2019 at our institution were retrospectively assessed for morbidity and mortality. Postoperative complications occurred in 196 patients (66.94%) in the elective group and 585 patients (75.4%) in the emergency group. The relatively low complication burden in the elective group was also evidenced by a significantly lower comprehensive complication index score (54.00 ± 37.36 vs. 59.25 ± 37.08, p = 0.040). The in-hospital mortality rates were 31% (91 of 293) and 38% (295 of 776) in the elective and emergency groups, respectively. This difference between the two groups was statistically significant (p = 0.035). In multivariate analysis, age, peripheral artery disease, pneumonia, thromboembolic events, ICU stay, ventilator dependence, acute kidney failure and liver failure were independent predictors of mortality. Our data show that patients undergoing EAE due to acute complications of major elective surgery tolerate the procedure relatively well compared with patients undergoing EAE due to primary high-risk abdominal emergencies.

Highlights

  • Irrespective of its etiology, emergency surgical abdominal exploration (EAE) is considered a highrisk procedure with mortality rates exceeding 20%

  • Patients undergoing EAE due to acute complications of major elective surgery tolerate the procedure relatively well compared with patients undergoing EAE due to primary major abdominal emergencies

  • The present study suggests that patient factors and excess medical complications contributed to the higher rate of mortality among high-risk abdominal emergency patients

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Summary

Introduction

Irrespective of its etiology, emergency surgical abdominal exploration (EAE) is considered a highrisk procedure with mortality rates exceeding 20%. The aim of this study was to evaluate differences in outcomes in patients who required EAE due to complications of complex elective abdominal procedures and those who required EAE due to high-risk primary abdominal emergencies. Despite continued efforts to improve preoperative patient management and operative techniques, complex elective abdominal surgical procedures still place patients at risk of postoperative complications that sometimes require emergency surgical intervention. These patients are at increased risk of mortality and prolonged hospital ­stay. Irrespective of its etiology, emergency surgical abdominal exploration (EAE) for primary major abdominal emergencies is considered a high-risk procedure with mortality rates exceeding 20%2–4 These patients experience a complication rate nearly triple the rate in elective s­ urgery. We hypothesized that given the standard preoperative care provided by a multidisciplinary team in preparation for elective surgery, patients undergoing

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