Abstract
xiii CHAPTER 1: INTRODUCTION 1 1.1. The cell cycle 1 1.2. Cell cycle exit 1 1.3. E2F family, pocket proteins and cell cycle control 2 1.4. Identification of the conserved DREAM and MMB complexes 5 1.5. Mammalian DREAM/MMB complexes assembly and regulation 8 1.6. DREAM, MMB, and cancer 12 1.7. Viral proteins, DREAM and cancer 14 1.8. Goals 16 CHAPTER 2: MATERIALS AND METHODS 17
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