Abstract
The effect of aspirin ingestion on the outcome of cataract formation in rats fed a galactose-containing diet was tested. Male, weanling Sprague Dawley rats were fed diets containing 35% galactose, and were pair-fed to rats eating similar diets but supplemented with 0.05% aspirin in their drinking water, or in their food. After 63 days, the level of free tryptophan in plasma was lower among rats given the aspirin. However, the rate of cataract formation did not differ between the experimental and control groups. Thus, aspirin did not influence the outcome of galactose-induced cataract formation in these rats.
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