Abstract

Abstract Changes in the pulmonary arterial tree after experimental aspiration pneumonia have been followed in the dog. Pulmonary arteriography demonstrated marked vasospasm and thrombosis of branches of the pulmonary artery 6 hours after aspiration in untreated animals. In animals treated by immediate positive-pressure ventilation for 6 hours after aspiration, these vascular changes did not occur. It is suggested that these vascular changes may be important events in the pathogenesis of aspiration pneumonia.

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