Abstract
Objective: to determine the time and development rate of acute lung injury (ALI) in severe brain injury (SBI) complicated by aspiration of gastric contents or blood. Subjects and methods. Twenty-nine patients aged 19 to 70 years, who had isolated SBI, of whom there were 24 males and 5 females), were examined. The patients were divided into 2 groups: those with aspiration of gastric contents (n=9) or blood (n=10). A control group included 10 patients with SBI without aspiration. A PiCCO plus device was used to determine pulmonary extravascular fluid. ALI was diagnosed in accordance with the recommendations of the Research Institute of General Reanimatology, Russian Academy of Medical Sciences. Results. SBI patients with aspiration of gastric contents or blood were found to have significantly increased pulmonary extravascular water (p<0.01) and a lower oxygenation index (<300), which correlated with each other. ALI was recorded in the first hours after injury in about 50% of cases in both patients with gastric contents aspiration and those with blood aspiration. Conclusion. In patients with SBI complicated by aspiration of gastric contents or blood, pulmonary extravascular fluid accumulation concurrent with other signs of injury may be regarded as a criterion for acute lung injury. Key words: severe brain injury, aspiration, acute lung lesion.
Highlights
Цель исследования — определить сроки и частоту развития острого повреждения легких при тяжелой черепно мозговой травме (ТЧМТ), осложненной аспирацией желудочного содержимого и крови
The patients were divided into 2 groups: those with aspiration of gastric contents (n=9) or blood (n=10)
ALI was diagnosed in accordance with the rec ommendations of the Research Institute of General Reanimatology, Russian Academy of Medical Sciences
Summary
Aspiration Induced Acute Lung Injury in Victims with Isolated Severe Brain Injury. Yu. Цель исследования — определить сроки и частоту развития острого повреждения легких при тяжелой черепно мозговой травме (ТЧМТ), осложненной аспирацией желудочного содержимого и крови. ОПЛ регистрируется в первые часы после трав мы, примерно, в 50% случаев как у больных с аспирацией желудочного содержимого, так и с аспирацией крови. У больных с ТЧМТ, осложненной аспирацией желудочного содержимого и крови, накопление внесосудистой жид кости в легких в совокупности с другими признаками повреждения может рассматриваться в качестве критерия острого повреждения легких. In patients with SBI complicated by aspiration of gastric contents or blood, pulmonary extravascular fluid accumulation concurrent with other signs of injury may be regarded as a criterion for acute lung injury. Цель исследования — определить сроки и частоту развития острого повреждения легких при черепно мозговой травме (ЧМТ), осложненной аспирацией же лудочного содержимого и крови
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