Abstract
Purpose: Serum markers have been used as tools in the diagnosis of inflammatory bowel diseases (Crohn's disease and ulcerative colitis) including anti-Saccharomyces cerevisiae antibodies (ASCA), neutrophil-specific nuclear autoantibodies (pANCA), and antibodies to outer membrane protein C of Escherichia coli (OmpC). It has been suggested that ASCA status correlates with aggressive phenotype in Crohn's disease (CD) including early age of onset, fibrostenosis, and internal fistulae. We performed a case-control study to evaluate the role of ASCA as a risk factor for early surgery in CD.
Full Text
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call