Abstract
Artificial enzymes based on the modification of a protein structure for the creation of new active catalytic sites have experienced a great boom in recent years. Multidisciplinary strategies of genetic engineering, chemical or chemical biological tools have been successfully described to synthetize them. However, a challenge has been focused on the creating of artificial enzymes with more than one active site. This could represent a new direction in the application of enzymatic tools in sustainable chemistry. Actually, only a few technologies have been described for designing artificial enzymes with two or multiple active sites. This review article underlines these most significant advances.
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More From: Current Opinion in Green and Sustainable Chemistry
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