Abstract

We performed a comprehensive search of the published literature in PubMed and Google Scholar to identify types, prevalence, etiology, clinical impact, and current methods for correction of various artifacts in optical coherence tomography angiography (OCTA) images. We found that the prevalence of OCTA image artifacts is fairly high. Artifacts associated with eye motion, misidentification of retinal layers, projections, and low optical coherence tomography signal are the most prevalent types. Artifacts in OCTA images are the major limitations of this diagnostic modality in clinical practice and identification of these artifacts and measures to mitigate them are essential for correct diagnosis and follow-up of patients.

Highlights

  • Optical coherence tomography angiography (OCTA) is an imaging method that provides threedimensional images from the microcirculation of the retina, choroid, and optic nerve head

  • The prevalence of artifacts varied based on the optical coherence tomography angiography (OCTA) device, setting, type of artifacts studied, and underlying disease [Table 1]

  • Artifacts are frequently observed on OCTA images and may occur during image acquisition, processing, and analysis.[52]

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Summary

Introduction

Optical coherence tomography angiography (OCTA) is an imaging method that provides threedimensional images from the microcirculation of the retina, choroid, and optic nerve head. Considering its noninvasive nature and fast acquisition time, OCTA has gained priority over fluorescein angiography (FA), the traditional. Previous studies have reported several types of artifacts impacting OCTA-derived metrics.[9,10,11,12,13,14] Overall, the prevalence of artifacts ranges from 72 to 100%.[13,14,15,16,17] various artifacts in OCTA images

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