Abstract
Arteriovenous graft (AVG) is artificially made with graft for hemodialysis in the patients with renal failure. Stenosis in the arterial or venous anastomosis of AVG results in its malfunction. Here, we made an AVG hemodynamic model with three different anastomotic angles (20°, 30°, 40°) and analyzed hemodynamic parameters such as velocity vectors, WSS and OSI in the arterial and venous anastomosis to find what helps in developing new surgical techniques to reduce stenosis in the anastomosis. Recirculation flow, low WSS and high OSI in the venous anastomosis were demonstrated in 30° and 40° models, and recirculation flow, high WSS and high OSI in the arterial anastomosis were shown in all models. Conclusively, higher anastomosis angle in the venous anastomosis cause stenosis, but stenosis in the arterial anastomosis happens irregardless of anastomosis angle.
Highlights
The incidence of renal failure is increasing due to increase in aged people and patients with diabetes mellitus
Higher anastomosis angle in the venous anastomosis cause stenosis, but stenosis in the arterial anastomosis happens irregardless of anastomosis angle
Arteriovenous graft (AVG) is a kind of arteriovenous fistulas, and it connects the artery and vein with graft to supply a large vessel for needling of hemodialysis
Summary
The incidence of renal failure is increasing due to increase in aged people and patients with diabetes mellitus. The limitation of kidney donors drives most patients with renal failure to dialysis, peritoneal dialysis or hemodialysis. Arteriovenous graft (AVG) is a kind of arteriovenous fistulas, and it connects the artery and vein with graft to supply a large vessel for needling of hemodialysis. Artery, vein and graft is used for computational mesh, and transient velocity profile of blood flow measured in ultrasonography is used for inlet and outlet boundary condition. Using this system, various simulations are carried out to analyze the effects of geometry of the artery, vein and graft on flow patterns and WSS and OSI distributions [4,5,6]
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