ARTERIAL HYPERTENSION AS A RISK FACTOR OF ISCHEMIC HEART DISEASE DESTABILIZATION (FRAGMENT OF RACSMI‑UZ STUDY)

Abstract

Background. Registries are the most accurate tool for assessing the status of real clinical practice. The registries help to identify deficiencies in the management of patients, to determine the most optimal ways to improve the quality of treatment. In 2015, the Republican Specialized Center of Cardiology organized and initiated the Registry of acute coronary syndrome (ACS) and acute myocardial infarction (AMI) in one of the districts of Tashkent city (RACSMI-Uz Registry). In the present work, which is a fragment of the RACSMI-Uz study, the main clinical and laboratory characteristics of patients with ACS/AMI were collected and analyzed, depending on the presence or absence of arterial hypertension (HTN). Design and methods . We analyzed the registry database of 432 patients who survived ACS/AMI. Results . In HTN patients survived after ACS/AMI, such accompanying pathologies as 1–2 stage obesity, myocardial infarction in past, type 2 diabetes mellitus, etc. were registered more often and the rate of stenotic (> 50 %) narrowing of the coronary arteries was greater. The heart rate > 80 beats/min was 1,5-times greater among HTN patients than among non-HTN subjects. Lipid metabolism in patients after ACS/AMI with concomitant HTN was characterized by hypertriglyceridemia and relatively safe low values of total cholesterol level. Compliance with medications was 2 times higher in HTN patients with ACS/AMI than among those without HTN.