Abstract
Changes of extracellular concentration of brain potassium [K+]e were studied in lightly anesthetized unrestrained rats with ion-selective K+-microelectrodes introduced into the cerebral cortex with a head-mounted microdrive system. Nociceptive stimuli elicited EEG arousal lasting for 47 sec on the averag which was accompained by an increase of [K+]e from 3.0 mM to 3.31 +/- 0.04 mM.
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