Abstract

Aromatic compounds represent important bulk and fine chemicals with numerous applications in the food, feed, cosmetics, pharmaceutical, and chemical industries. These are currently produced from non-renewable petroleum resources via chemical conversion with high environmental load or via inefficient extraction from natural plant resources. To cope with such problems, microbial production of aromatic compounds from abundant and renewable sugar feedstocks has recently received great attention as an eco-friendly and efficient alternative to producing aromatic compounds. In this context, the product spectrum of Corynebacterium glutamicum has recently extended to industrially valuable aromatic compounds ranging from various benzene/benzoate derivatives to more intricate plant polyphenols, some of which could be produced from sugars with markedly high productivities. This chapter summarizes recent advances in the metabolic engineering of C. glutamicum for the production of valuable aromatic and related compounds.

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