Abstract
The pharmacological properties of arnica flowers are mainly due to the action of sesquiterpene lactones and flavonoids. The mechanism of the anti-inflammatory action of Arnicae flos (in vitro studies) is based on the inhibition of the release of pro-inflammatory factors: NF-κB, NF-AT and metabolic products of arachidonic acid. This herbal substance is used only externally in blunt injuries (contusions, sprains, bruises), as well as in muscle and rheumatic pains. Strong antimicrobial properties, equal to the activity of antibiotics, justify the use of arnica flowers in dermatoses.
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