Abstract

Elevated cholesterol is a major risk factor for atherosclerosis and coronary heart disease, and its control remains poor. Diet and exercise may not achieve LDL-C goals, particularly in high-risk patients. Statins are first-line treatment for lowering LDL-C. Recent ACC/AHA guidelines focus on groups benefiting the most from a statin, as well as using higher dose statins rather than a low-dose statin in combination with other cholesterol-lowering agents. Statin monotherapy will be inadequate to get half of treated patients to LDL-C goal, necessitating add-on therapy. Combining a statin with a bile acid sequestrant, fibrate or ezetimibe can help achieve lipid goals, and a bile acid sequestrant has the unique ability to reduce LDL-C, while improving glycemic control in patients with diabetes.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.