Abstract

Background: Tooth extraction can cause wound in hard tissue and soft tissue inside oral cavity. Wound healing process involves cell proliferation especially fibroblast cells. To accelerate fibroblast cell proliferation alternative substance that can accelerates wound healing process is needed which is arabica coffee fruit skin. Arabica coffee fruit skin contains substances such as polyphenols, tannin, chlorogenic acid, and caffeine expected to be able to stimulate fibroblast cells amount. Objective: To understand arabica coffee fruit skin potential towards increase in number of fibroblast cells on the socket after tooth extraction. Method: The design of this research was post test only control group with sample size of 24 wistar mouse. The samples used were divided into two groups which are control and treatment group. Then treatment was given in 3 days, 5 days, and 7 days. Then they were decapitated to undergo tissue processing with HE coloring and post tooth extraction socket fibroblast cells counting. Acquired data then analyzed used One Way ANOVA and LSD test. Result: Fibroblast cell amount increased significantly (p<0.05) in treatment group compared to control group. Conclusion: Arabica coffee fruit skin potentially increase fibroblast cells amount in socket post tooth extraction of male wistar mouse. Keywords: tooth extraction; wound healing; fibroblast cells

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.