Ağır preeklampsi ve eklampsi nedeni ile magnezyum sülfat infüzyonu uygulanan gebelerin perinatal sonuçlarının incelenmesi

Abstract

Objective: In this study, we aimed to analyze the perinatal outcomes of the pregnant women who were applied magnesium sulfate due to the diagnosis of severe preeclampsia and eclampsia in our clinic. Methods: The patients hospitalized in our clinic and administered with magnesium sulfate due to diagnosis of severe preeclampsia and eclampsia between January 2011 and January 2015 were included in this retrospective study. The data of perinatal outcomes of the patients were reviewed retrospectively through hospital’s medical records. Ablatio placentae, oligohydramnios, maternal acute renal failure, maternal neurological deficits, intracranial hemorrhage, which are the maternal complications of preeclampsia and eclampsia, and fetal intracranial hemorrhage, fetal growth retardation, newborn’s intense care need and neonatal necrotizing enterocolitis development, which are the potential fetal complications of preeclampsia and eclampsia, were considered as poor perinatal outcomes. Results: A total of 207 patients were included in the study. When hospital records were reviewed, it was seen that 17 cases admitted to the hospital after eclamptic seizure, and 54 cases had eclamptic seizure when undergoing magnesium sulfate treatment due to the diagnosis of severe preeclampsia. Mean week of gestation was 32±2.4 in the severe preeclampsia group and 30±1.5 in the eclampsia group. While maternal death associated with disseminated intravascular coagulopathy (DIC) occurred in one of the 17 patients admitted with eclampsia diagnosis, a mass was identified in the frontal lobe in one patient. In 8 patients, various levels of HELLP syndrome developed. Mean hospitalization period of the patients with severe preeclampsia was 4±1.7 days while it was 6±2.2 days in patients with eclampsia. Conclusion: The presence of severe preeclampsia and eclampsia is associated with poor maternal and fetal perinatal outcomes despite the appropriate treatment and close follow-up.