Abstract
AbstractMaldi-TOF mass spectrometry represents a major technical advance and an alternative to the relatively laborious and complex identification of dermatophytes by macroscopic and microscopic morphology, which requires highly skilled mycologists, an expertise that is becoming scarce in medical analysis laboratories. Provided that the dermatophyte has been successfully isolated in culture and that an adequate (i.e., comprehensive and in keeping with the current nomenclature) Maldi-TOF mass spectrometry reference spectra database is available, Maldi-TOF MS is relatively cheaper and offers a comparable accuracy to that of DNA sequencing for the identification of dermatophytes. The use of this new identification tool is likely to support to the ongoing dermatophytes taxonomic clarification. The taxonomic clarification will further contribute to a better understanding of the epidemiology of dermatophytes and the impact of the species involved on the outcomes of patients with dermatophytoses.
Published Version
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