Abstract

Due to the increase in the number of patients who died as a result of the SARS-CoV-2 virus around the world, researchers are working tirelessly to find technological solutions to help doctors in their daily work. Fast and accurate Artificial Intelligence (AI) techniques are needed to assist doctors in their decisions to predict the severity and mortality risk of a patient. Early prediction of patient severity would help in saving hospital resources and decrease the continual death of patients by providing early medication actions. Currently, X-ray images are used as early symptoms in detecting COVID-19 patients. Therefore, in this research, a prediction model has been built to predict different levels of severity risks for the COVID-19 patient based on X-ray images by applying machine learning techniques. To build the proposed model, CheXNet deep pre-trained model and hybrid handcrafted techniques were applied to extract features, two different methods: Principal Component Analysis (PCA) and Recursive Feature Elimination (RFE) were integrated to select the most important features, and then, six machine learning techniques were applied. For handcrafted features, the experiments proved that merging the features that have been selected by PCA and RFE together (PCA + RFE) achieved the best results with all classifiers compared with using all features or using the features selected by PCA or RFE individually. The XGBoost classifier achieved the best performance with the merged (PCA + RFE) features, where it accomplished 97% accuracy, 98% precision, 95% recall, 96% f1-score and 100% roc-auc. Also, SVM carried out the same results with some minor differences, but overall it was a good performance where it accomplished 97% accuracy, 96% precision, 95% recall, 95% f1-score and 99% roc-auc. On the other hand, for pre-trained CheXNet features, Extra Tree and SVM classifiers with RFE achieved 99.6% for all measures.

Highlights

  • Predicting the severity risk of any disease at an early stage is a crucial task and has many effects, like reducing the mortality rate, consuming hospital resources, and supporting doctors in their decision making.In the current critical period, during the spread of coronavirus around the world and the increasing number of patients and deaths, the number of COVID-19 patients reached nearly 230 million while the number of deaths was 4.7 million around the world till during writing this research, according to statistics from Johns Hopkins University [1].The associate editor coordinating the review of this manuscript and approving it for publication was Derek Abbott .The United States is the head of the countries, followed by Brazil, India, France, Russia, Italy, and many other countries

  • The experimental results are presented in the following tables have meaningful column names: the ‘‘All’’ column means using all extracted features; the ‘‘Principal Component Analysis (PCA)’’ and ‘‘Recursive Feature Elimination (RFE)’’ columns denote the results of the selected features by PCA and RFE techniques individually; and the ‘‘(PCA + RFE)’’ column shows the results of the combined features of PCA and RFE techniques together

  • This study proposes a new predictive framework for the severity and mortality risk of COVID-19 patients to help doctors, hospitals, and medical facilities in their decision making about which patients need to get attention first before others, and at the same time, to keep hospitals’ resources for high-risk priority patients

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Summary

Introduction

The United States is the head of the countries, followed by Brazil, India, France, Russia, Italy, and many other countries. The reasons behind this growth in numbers are the high prevalence of COVID-19, late diagnosis, and lack of resources in many hospitals to absorb this pandemic. Predicting the severity risk of COVID-19 patients is a critical task and has many positive outcomes, such as providing the required health care for each patient according to his severity, good consumption of hospital resources that give the highest priority to the high-risk patient, and assisting doctors in making their decisions that will lead to improvement in the patient’s treatment

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