Abstract
Molecular imaging is an emerging technology in life science and biomedical engineering, which can directly measure the distribution and changes of drugs and compounds in vivo, explore specific targets and biological processes at a cellular and molecular level. Compared to conventional imaging modalities, molecular imaging is noninvasive, real-time, specific, sensitive and of high resolution, and thus has great promises in drug discovery and development. By selecting candidate drugs that are most likely to be successful or halting those unnecessary processes, this new technique will revolutionize our understanding of preclinical and clinical pharmacokinetics and pharmacodynamics. Here, we present some important applications of molecular imaging in the key stages of drug discovery and development. Key words: Molecular imaging; Drug discovery and development; Imaging technology; Imaging biomarker
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