Applications of bond energies of transition-metal-ligand σ-bonds inC–H bond activation

Abstract

<p indent="0mm">Because of its good step- and atom-economy, transition-metal-catalyzed C–H bond activation has been a prevailing method to construct molecular complexity. Thermodynamic knowledge of the corresponding metal-ligand complex is beneficial to deep understanding of the catalytic mechanism as well as rational design of new catalysts and development of new reactions. However, a summary of thermodynamic studies relevant to metal-ligand σ-bonds is in vacancy. This review outlines the development history of this area. Several examples are given to illustrate the applications of these thermodynamic parameters in analyzing the feasibility and selectivity of the processes mediated by transition-metals.