Abstract

Objective To explore the usage of Shi Jie Yin (Monosialotetrahexosylganglioside) with early comprehensive nursing intervention on the potential development of premature children.Methods 320 cases of premature children were randomly divided into intervention group and control group.The intervention group with 160 cases was given Shi Jie Yin with early rich environment intervention and comprehensive rehabilitation functional training in addition to conventional treatment.Control group only received conventional treatment,parental guidance and assessments.After discharging,children in both groups were followed up till 5 years old according to the 0 ~3 years outline of intellectual development in children and education programs.Results Scores of intervention group were significantly higher than the control group in behavioral and general condition according to NBNA [ (9.32 ± 0.33) and (5.94 ± 0.83 ) for intervention group,(6.35 ± 1.35 ) and (4.39 ± 0.42) for the control group; t =9.573,3.590,respectively; P < 0.0 1 ].In the month with completed neurological and psychological developments,children in control group showed significantly less raising head at the supine position,upright of head,turn over,conscious pronouncing and laughing,grabbing toys with fingers,sitting steady with free hands and crawling than those of the intervention group (t =3.29,4.27,3.62,2.98,4.62,4.52,4.51,respectively ;P <0.01 ).The CDCC scale monitoring of the two groups included development index (MDI) and physical development index (PDI).Intervention group had higher scores in both indexes than the control group[ (95.46 ± 12.35 ) and ( 98.87 ± 12.20) vs ( 79.12 ± 1 4.71 ) and ( 84.03 ± 1 3.37 ) ; t =5.761,6.832,respectively;P < 0.01 ].Comparing two groups of the development of intelligent energy region and the total developmental quotient,the intervention group was significantly higher than the control group ( P <0.01 ).For retardation and the incidence of complications,the intervention group was significantly lower than the control group ( P < 0.05 ).Conclusions Application of Shi Jie Yin with early comprehensive nursing intervention in the potential development of premature children,together with comprehensive system of rehabilitation functional training,adequate treatment and follow-up treatment could reduce the incidence of cerebral palsy and mental retardation and complications,promote the overall development potential of premature children,and improve the quality of survival of premature children and population quality. Key words: Medication treatment; Early nursing intervention; Premature children; Potential development

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