Application of PSMA ligands PET imaging in the diagnosis and treatment of non-prostate tumors

Abstract

Prostate specific membrane antigen (PSMA) is a hot topic in molecular imaging research of prostate cancer. However, non-prostate related PSMA can also be expressed in physiological tissues and different benign and malignant diseases, especially in tumor-associated endovascular endothelial cells. Related clinical studies have demonstrated the staging potential of PSMA ligands PET imaging in non-prostate tumors. This article summarizes the application of PSMA ligands PET imaging in the diagnosis and treatment of non-prostate tumors. Key words: Prostate-specific membrane antigen; Positron-emission tomography; Trends