Abstract
This article explores the value of wall F-FDG PET/Cr imaging in the diagnosis of thyroid cancer, studies its ability to distinguish benign and malignant thyroid lesions, and seeks ways to improve the accuracy of diagnosis. The normal control group selected 40 patients who came to our center for physical examination. In the normal control group, the average value of the standard uptake value of both sides of the thyroid was used as the SUV of the thyroid gland and the highest SUV value of the patient's lesion (SUV max) represented the SUV of the lesion. After injection of imaging agent 18F-FD1G, routine imaging was performed at 1h, time-lapse imaging was performed at 2.5 h, and the changes with conventional imaging were compared to infer the benign and malignant lesions. We used SPSS software to carry out statistical analysis, respectively, carrying out analysis of variance, paired t-test, independent sample t-test, and linear correlation analysis. In the thyroid cancer group, 87.5% of the delayed imaging SUV was higher than the conventional imaging SUV, while 83.33% of the benign disease group had a lower SUV than the conventional imaging SUV. 18F-FDG PET/CT imaging has higher sensitivity and specificity for the diagnosis of recurrence or metastasis in patients with Tg positive. However, it has lower sensitivity and specificity for the diagnosis of 131I-Dx-WBS negative DTC and 18F-FDG PET/CT. The specificity increases with the increase of serum Tg level. The above results confirm that 18F-FDG PET/CT imaging is of great significance for the diagnosis of recurrence or metastasis in patients; with PET/CT imaging, the results changed 16.13% of the Tg-positive and 131I-Dx-WBS negative DTC patients' later treatment decision. The decision-making and curative effect evaluation have certain value.
Highlights
Research ArticleApplication of Pet-CT Fusion Deep Learning Imaging in Precise Radiotherapy of Thyroid Cancer
Academic Editor: Robertas Damasevicius is article explores the value of wall F-FDG PET/Cr imaging in the diagnosis of thyroid cancer, studies its ability to distinguish benign and malignant thyroid lesions, and seeks ways to improve the accuracy of diagnosis. e normal control group selected 40 patients who came to our center for physical examination
In the thyroid cancer group, 87.5% of the delayed imaging standard uptake value (SUV) was higher than the conventional imaging SUV, while 83.33% of the benign disease group had a lower SUV than the conventional imaging SUV. 18F-FDG PET/CT imaging has higher sensitivity and specificity for the diagnosis of recurrence or metastasis in patients with Tg positive
Summary
Application of Pet-CT Fusion Deep Learning Imaging in Precise Radiotherapy of Thyroid Cancer. 18F-FDG PET/CT whole-body imaging has been used to distinguish benign and malignant tumors, to detect curative effects, to detect metastases, and to determine prognosis, which has achieved important clinical value [7]. Shakeel et al [12] retrospectively analyzed the 18F-FDG PET/CT whole-body imaging of 4136 subjects without a history of thyroid disease and found 45 cases (35 cases of women, 10 cases of men) of incidental thyroid tumors; the detection rate was 1.1%. Because PET imaging can directly detect tumor foci through abnormalities in local metabolic activity, it has a higher specificity, which is helpful for the identification of other benign lesions, and can detect metastases in other organs and soft tissues at the same time, which is helpful to guide the clinical selection of a more appropriate treatment plan. E diameter of the thyroid lesion was measured by CT image
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