Abstract

ObjectiveTo study the changes in retinal and choroidal vessels in patients with coronary artery stenosis via optical coherence tomography angiography (OCTA). MethodsA total of 100 subjects were enrolled in this study and divided into two groups:the observation group consisted of 50 patients with angina who were first diagnosed with coronary artery stenosis, and the control group consisted of 50 healthy adults without angina symptoms. All of the subjects underwent OCTA to investigate changes in retinochoroidal vessel density in patients with a first diagnosis of coronary artery stenosis. The parameters included superficial capillary plexus density (SCD), deep capillary plexus density (DCD), retinal peripapillary capillary plexus density(RPD), the choroidal vascular index (CVI), and the macular foveal avascular zone(FAZ area, perimeter, acircularity index, FD-300 vessel density). ResultsSCD and DCD in the coronary artery stenosis group were lower than those in the control group (P=0.045 and P=0.034, respectively), the CVI was lower than that in the control group (P=0.029), the FAZ perimeter and acircularity index were greater than those in the control group (P=0.003,P=0.024). Logistic regression and ROC curve analysis revealed that FAZ perimeter was the most significant risk factor for predicting coronary artery stenosis (P=0.005, AUC=0.664), and the cut-off value for FAZ perimeter was 2.065 mm. ConclusionsIn patients with a first diagnosis of coronary artery stenosis, both retinal and choroidal blood flow are reduced. FAZ perimeter is a risk factor for predicting the occurrence of coronary artery stenosis.

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.