Application of new blood-saving extracorporeal circulation circuits in open heart surgery

Abstract

Objective To explore the blood-saving and conservation effect and clinical prognosis of extracorporeal circulation circuits designed individually by using medical polymeric materials for adults and infants in cardiac surgical procedures. Methods A total of 41 new extracorporeal circulation circuits designed based on the operation requirements, including 20 for adults and 21 for infants, were applied on adults and infants (body weight less than 10 kg), and the results were compared with that of the conventional circuits on adults (20) and infants (19) respectively. Total priming volume, priming and intraoperative blood products consumption, pump pressure, intraoperative blood hemoglobin (Hb) level, free Hb (f-Hb), platelet (Plt) count, mixed venous oxygen saturation (SvO2), colloid osmotic pressure (COP), lactate (Lac) level, Hb level after modified ultrafiltration, endotracheal intubation time and ICU time were all collected in two groups. Results Priming volume, priming and intraoperative blood consumption and f-Hb level in the blood-saving and conservation circuits group were significantly lower than that of conventional circuits group (P 0.05) between the two groups in pump pressure, intraoperative blood Hb level, Plt, SvO2, COP, Lac level, Hb level after modified ultrafiltration, endotracheal intubation time and ICU time. Conclusions The minimized blood conservation extracorporeal circulation circuit plays an important role in reducing priming volume and blood transfusion. It maintains a normal level of hemodynamics, oxygenation and tissue perfusion level during cardiopulmonary bypass in cardiac surgery for adults and infants. Red blood cell destruction can be reduced by improving blood compatibility, and physical data are all stabilized intra and post operation. This new circuit is secure, with its better outcome, expected in application. Key words: Extracorporeal circulation; Infant; Blood-saving circuit